Uso de solventes Eutéticos profundos na extração de constituintes químicos de Miconia albicans (SW.) TRIANA

Abstract

For a long time, human beings have used plant species to treat and cure various pathologies. Although several substances have already been isolated, many compounds are still unknown due to the immense biological diversity present in the plant kingdom. These compounds from vegetables may benefit human health, such as antioxidant action. Antioxidants are compounds that can prevent or inhibit the impact of free radicals associated with the development of chronic diseases like diabetes and cancer. Generally, the extraction of these bioactive compounds is carried out by liquid-liquid or solid-liquid extractions using solvents that usually have harmful effects on the environment. Thus, the dissertation presents the study divided into two articles. The first aims to compare the efficiency of the extraction of eutectic and conventional solvents in the extraction of phenolic bioactive, flavonoids, and antioxidants of Miconia albicans (Sw.) Triana. In this context, eutectic solvents were prepared and characterized and evaluated the antioxidant capacity by the method of sequestration with the free radical DPPH, phenolic and flavonoid contents, in addition to the chemical characterization by the identification of phenolic acids by HPLC- DAD. In the second article, we sought to compare the extraction of bioactives from the commercialized M. albicans versus the native plant collected in several regions of the Atlantic Forest South of Bahia. Thus, the results indicated that the extraction by using the deep eutectic solvent (DES) is more effective in evaluating the constituents in M. albicans, a cleaner and greener alternative than conventional solvents.